Difference between revisions of "YlaM"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylaL]]'', ''[[ylaN]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylaL]]'', ''[[ylaN]]''
 
|-
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU14830 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU14830 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU14830 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU14830 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU14830 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU14830 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ylaM_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ylaM_context.gif]]

Revision as of 10:07, 14 May 2013

  • Description: glutaminase, high affinity for glutamine

Gene name ylaM
Synonyms
Essential no
Product glutaminase
Function glutamine degradation
Gene expression levels in SubtiExpress: ylaM
MW, pI 33 kDa, 5.676
Gene length, protein length 927 bp, 309 aa
Immediate neighbours ylaL, ylaN
Sequences Protein DNA DNA_with_flanks
Genetic context
YlaM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YlaM expression.png
























Categories containing this gene/protein

utilization of amino acids, sporulation proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU14830

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-glutamine + H2O = L-glutamate + NH3 (according to Swiss-Prot)
  • Protein family: glutaminase family (according to Swiss-Prot)
  • Paralogous protein(s): GlsA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Greg Brown, Alex Singer, Michael Proudfoot, Tatiana Skarina, Youngchang Kim, Changsoo Chang, Irina Dementieva, Ekaterina Kuznetsova, Claudio F Gonzalez, Andrzej Joachimiak, Alexei Savchenko, Alexander F Yakunin
Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis.
Biochemistry: 2008, 47(21);5724-35
[PubMed:18459799] [WorldCat.org] [DOI] (I p)