Difference between revisions of "ZnuC"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[znuA]]'', ''[[znuB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[znuA]]'', ''[[znuB]]''
 
|-
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02860 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02860 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02860 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02860 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02860 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02860 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ycdI_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ycdI_context.gif]]

Revision as of 09:25, 14 May 2013

Gene name znuC
Synonyms ycdI
Essential no
Product ABC transporter for zinc (ATP-binding protein)
Function zinc uptake
Gene expression levels in SubtiExpress: znuC
Interactions involving this protein in SubtInteract: ZnuC
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 26 kDa, 8.198
Gene length, protein length 693 bp, 231 aa
Immediate neighbours znuA, znuB
Sequences Protein DNA DNA_with_flanks
Genetic context
YcdI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ZnuC expression.png




























Categories containing this gene/protein

ABC transporters, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), membrane proteins

This gene is a member of the following regulons

Zur regulon

The gene

Basic information

  • Locus tag: BSU02860

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: associated to the membrane (via ZnuB) PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
    • Zur: transcription repression in the presence of zinc PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Mitsuo Ogura
ZnuABC and ZosA zinc transporters are differently involved in competence development in Bacillus subtilis.
J Biochem: 2011, 150(6);615-25
[PubMed:21813502] [WorldCat.org] [DOI] (I p)

Ahmed Gaballa, Tao Wang, Rick W Ye, John D Helmann
Functional analysis of the Bacillus subtilis Zur regulon.
J Bacteriol: 2002, 184(23);6508-14
[PubMed:12426338] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)

A Gaballa, J D Helmann
Identification of a zinc-specific metalloregulatory protein, Zur, controlling zinc transport operons in Bacillus subtilis.
J Bacteriol: 1998, 180(22);5815-21
[PubMed:9811636] [WorldCat.org] [DOI] (P p)