FeuC

• Description: ABC transporter for the siderophores Fe-enterobactin and Fe-bacillibactin (integral membrane protein)
  
  

Gene name	feuC
Synonyms
Essential	no
Product	ABC transporter for the siderophores Fe-enterobactin and Fe-bacillibactin (integral membrane protein)
Function	acquisition of iron
Gene expression levels in SubtiExpress: feuC
Interactions involving this protein in SubtInteract: FeuC
Metabolic function and regulation of this protein in SubtiPathways: Stress, Metal ion homeostasis
MW, pI	42 kDa, 10.435
Gene length, protein length	1182 bp, 394 aa
Immediate neighbours	ybbA, feuB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Btr regulon, CitB regulon, Fur regulon

The gene

Basic information

• Locus tag: BSU01610

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: FecCD subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YusV-(FeuB-FeuC)-FeuA PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: P40411

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: feuA-feuB-feuC-ybbA PubMed

• Expression browser: feuC PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed in the presence of iron (Fur, CitB) PubMed
  • induced in the presence of iron chelators bacillibactin or enterobactin (Btr) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed
  • CitB: binding to the iron responsive element in the absence of iron
  • Btr: transcription activation in the presence of the co-activators bacillibactin or enterobactin PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: