Difference between revisions of "ParA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || forespore chromosome partitioning /<br/> negative regulation of sporulation initiation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || forespore chromosome partitioning /<br/> negative regulation of sporulation initiation
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU40970 soj]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU40970 soj]
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/Soj Soj]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/Soj Soj]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spo0J]]'', ''[[yyaB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spo0J]]'', ''[[yyaB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB16134&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU40970 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU40970 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU40970 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:soj_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:soj_context.gif]]

Revision as of 14:21, 13 May 2013

  • Description: ATPase, centromere-like function involved in forespore chromosome partitioning / negative regulation of sporulation initiation

Gene name soj
Synonyms spo0JA
Essential no
Product negative regulator of sporulation initiation
Function forespore chromosome partitioning /
negative regulation of sporulation initiation
Gene expression levels in SubtiExpress: soj
Interactions involving this protein in SubtInteract: Soj
MW, pI 27 kDa, 4.903
Gene length, protein length 759 bp, 253 aa
Immediate neighbours spo0J, yyaB
Sequences Protein DNA Advanced_DNA
Genetic context
Soj context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Soj expression.png
























Categories containing this gene/protein

DNA condensation/ segregation, sporulation/ other, membrane proteins

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

  • Locus tag: BSU40970

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Protein family: parA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
    • Spo0J inhibits Soj dimerization and concomitant DNA-binding activity by stimulating Soj ATPase activity PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Tsutomu Katayama, Shogo Ozaki, Kenji Keyamura, Kazuyuki Fujimitsu
Regulation of the replication cycle: conserved and diverse regulatory systems for DnaA and oriC.
Nat Rev Microbiol: 2010, 8(3);163-70
[PubMed:20157337] [WorldCat.org] [DOI] (I p)

Original publications

Additional publications: PubMed