Difference between revisions of "QdoR"
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of quercetin utilization | |style="background:#ABCDEF;" align="center"|'''Function''' || control of quercetin utilization | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU39990 qdoR] |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 20 kDa, 6.111 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 20 kDa, 6.111 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[qdoI]]'', ''[[yxnA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[qdoI]]'', ''[[yxnA]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU39990 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU39990 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU39990 Advanced_DNA] |
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Revision as of 14:17, 13 May 2013
| Gene name | qdoR |
| Synonyms | yxaF |
| Essential | no |
| Product | transcriptional regulator |
| Function | control of quercetin utilization |
| Gene expression levels in SubtiExpress: qdoR | |
| MW, pI | 20 kDa, 6.111 |
| Gene length, protein length | 573 bp, 191 aa |
| Immediate neighbours | qdoI, yxnA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
transcription factors and their control, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)
This gene is a member of the following regulons
The QdoR regulon:
The gene
Basic information
- Locus tag: BSU39990
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): LmrA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: flavonoids such as quercetin act as molecular inducers and result in release from DNA targets PubMed
Database entries
- Structure: 1SGM
- UniProt: P42105
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: qdoR PubMed
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Yasutaro Fujita, University of Fukuyama, Japan
Your additional remarks
References
Kazutake Hirooka, Yasutaro Fujita
Identification of aromatic residues critical to the DNA binding and ligand response of the Bacillus subtilis QdoR (YxaF) repressor antagonized by flavonoids.
Biosci Biotechnol Biochem: 2011, 75(7);1325-34
[PubMed:21737930]
[WorldCat.org]
[DOI]
(I p)
Kazutake Hirooka, Satoshi Kunikane, Hiroshi Matsuoka, Ken-Ichi Yoshida, Kanako Kumamoto, Shigeo Tojo, Yasutaro Fujita
Dual regulation of the Bacillus subtilis regulon comprising the lmrAB and yxaGH operons and yxaF gene by two transcriptional repressors, LmrA and YxaF, in response to flavonoids.
J Bacteriol: 2007, 189(14);5170-82
[PubMed:17483215]
[WorldCat.org]
[DOI]
(P p)
Ken-Ichi Yoshida, Izumi Ishio, Eishi Nagakawa, Yoshiyuki Yamamoto, Mami Yamamoto, Yasutaro Fujita
Systematic study of gene expression and transcription organization in the gntZ-ywaA region of the Bacillus subtilis genome.
Microbiology (Reading): 2000, 146 ( Pt 3);573-579
[PubMed:10746760]
[WorldCat.org]
[DOI]
(P p)
