Difference between revisions of "CtpB"
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigK]] activation | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigK]] activation | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35240 ctpB] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 52 kDa, 8.641 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 52 kDa, 8.641 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[swrAA/2]]'', ''[[ftsX]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[swrAA/2]]'', ''[[ftsX]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35240 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35240 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35240 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yvjB_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yvjB_context.gif]] | ||
Revision as of 13:58, 13 May 2013
- Description: carboxy-terminal processing serine protease, cleaves SpoIVFA, this results in processing of pro-SigK
| Gene name | ctpB |
| Synonyms | yvjB |
| Essential | no |
| Product | carboxy-terminal processing serine protease, cleaves SpoIVFA |
| Function | control of SigK activation |
| Gene expression levels in SubtiExpress: ctpB | |
| MW, pI | 52 kDa, 8.641 |
| Gene length, protein length | 1440 bp, 480 aa |
| Immediate neighbours | swrAA/2, ftsX |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
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Contents
Categories containing this gene/protein
proteolysis, sigma factors and their control, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35240
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): CtpA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O35002
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: ctpB (according to DBTBS)
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Nathalie Campo, David Z Rudner
SpoIVB and CtpB are both forespore signals in the activation of the sporulation transcription factor sigmaK in Bacillus subtilis.
J Bacteriol: 2007, 189(16);6021-7
[PubMed:17557826]
[WorldCat.org]
[DOI]
(P p)
Nathalie Campo, David Z Rudner
A branched pathway governing the activation of a developmental transcription factor by regulated intramembrane proteolysis.
Mol Cell: 2006, 23(1);25-35
[PubMed:16818230]
[WorldCat.org]
[DOI]
(P p)
Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325]
[WorldCat.org]
[DOI]
(P p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Qi Pan, Richard Losick, David Z Rudner
A second PDZ-containing serine protease contributes to activation of the sporulation transcription factor sigmaK in Bacillus subtilis.
J Bacteriol: 2003, 185(20);6051-6
[PubMed:14526016]
[WorldCat.org]
[DOI]
(P p)
