Difference between revisions of "TrxB"
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|style="background:#ABCDEF;" align="center"|'''Function''' || keeps thioredoxin in the reduced state | |style="background:#ABCDEF;" align="center"|'''Function''' || keeps thioredoxin in the reduced state | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU34790 trxB] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 34 kDa, 4.99 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 34 kDa, 4.99 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yvcI]]'', ''[[cwlO]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yvcI]]'', ''[[cwlO]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU34790 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU34790 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU34790 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:trxB_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:trxB_context.gif]] | ||
Revision as of 13:56, 13 May 2013
- Description: thioredoxin reductase (NADPH)
| Gene name | trxB |
| Synonyms | yvcH |
| Essential | yes PubMed |
| Product | thioredoxin reductase (NADPH) |
| Function | keeps thioredoxin in the reduced state |
| Gene expression levels in SubtiExpress: trxB | |
| MW, pI | 34 kDa, 4.99 |
| Gene length, protein length | 948 bp, 316 aa |
| Immediate neighbours | yvcI, cwlO |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
electron transport/ other, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU34790
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Thioredoxin + NADP+ = thioredoxin disulfide + NADPH (according to Swiss-Prot)
- Protein family: class-II pyridine nucleotide-disulfide oxidoreductase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P80880
- KEGG entry: [2]
- E.C. number: 1.8.1.9
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796]
[WorldCat.org]
[DOI]
(I p)
Michiko M Nakano, Ann Lin, Cole S Zuber, Kate J Newberry, Richard G Brennan, Peter Zuber
Promoter recognition by a complex of Spx and the C-terminal domain of the RNA polymerase alpha subunit.
PLoS One: 2010, 5(1);e8664
[PubMed:20084284]
[WorldCat.org]
[DOI]
(I e)
Shunji Nakano, Michiko M Nakano, Ying Zhang, Montira Leelakriangsak, Peter Zuber
A regulatory protein that interferes with activator-stimulated transcription in bacteria.
Proc Natl Acad Sci U S A: 2003, 100(7);4233-8
[PubMed:12642660]
[WorldCat.org]
[DOI]
(P p)
