Difference between revisions of "MdtP"
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|style="background:#ABCDEF;" align="center"|'''Function''' || multidrug resistance | |style="background:#ABCDEF;" align="center"|'''Function''' || multidrug resistance | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU32880 mdtP] |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 57 kDa, 9.836 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 57 kDa, 9.836 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mdtR]]'', ''[[yusQ]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mdtR]]'', ''[[yusQ]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU32880 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU32880 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU32880 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yusP_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yusP_context.gif]] | ||
Revision as of 13:48, 13 May 2013
- Description: multidrug-efflux transporter
| Gene name | mdtP |
| Synonyms | yusP |
| Essential | no |
| Product | multidrug-efflux transporter |
| Function | multidrug resistance |
| Gene expression levels in SubtiExpress: mdtP | |
| MW, pI | 57 kDa, 9.836 |
| Gene length, protein length | 1623 bp, 541 aa |
| Immediate neighbours | mdtR, yusQ |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
| |
Contents
Categories containing this gene/protein
transporters/ other, resistance against toxins/ antibiotics, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: EmrB family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane (according to Swiss-Prot), membrane associated PubMed
Database entries
- Structure:
- UniProt: O32182
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant: BP70 (spc) available in Fabian Commichau's lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ji-Yun Kim, Takashi Inaoka, Kazutaka Hirooka, Hiroshi Matsuoka, Makiko Murata, Reiko Ohki, Yoshikazu Adachi, Yasutaro Fujita, Kozo Ochi
Identification and characterization of a novel multidrug resistance operon, mdtRP (yusOP), of Bacillus subtilis.
J Bacteriol: 2009, 191(10);3273-81
[PubMed:19286808]
[WorldCat.org]
[DOI]
(I p)
Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711]
[WorldCat.org]
[DOI]
(I p)
