Difference between revisions of "MdtR"
| Line 14: | Line 14: | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of the multidrug-resistance ''[[mdtR]]-[[mdtP]]'' operon | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of the multidrug-resistance ''[[mdtR]]-[[mdtP]]'' operon | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU32870 mdtR] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 6.376 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 6.376 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yusN]]'', ''[[mdtP]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yusN]]'', ''[[mdtP]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU32870 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU32870 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU32870 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yusO_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yusO_context.gif]] | ||
Revision as of 13:48, 13 May 2013
| Gene name | mdtR |
| Synonyms | yusO |
| Essential | no |
| Product | transcription repressor (MarR family) |
| Function | regulation of the multidrug-resistance mdtR-mdtP operon |
| Gene expression levels in SubtiExpress: mdtR | |
| MW, pI | 17 kDa, 6.376 |
| Gene length, protein length | 465 bp, 155 aa |
| Immediate neighbours | yusN, mdtP |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
| |
Contents
Categories containing this gene/protein
transcription factors and their control, resistance against toxins/ antibiotics
This gene is a member of the following regulons
The MdtR regulon:
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 1S3J
- UniProt: O32181
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism: repression by MdtR PubMed
- Additional information:
Biological materials
- Mutant: GP1115 (spc), available in Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ji-Yun Kim, Takashi Inaoka, Kazutaka Hirooka, Hiroshi Matsuoka, Makiko Murata, Reiko Ohki, Yoshikazu Adachi, Yasutaro Fujita, Kozo Ochi
Identification and characterization of a novel multidrug resistance operon, mdtRP (yusOP), of Bacillus subtilis.
J Bacteriol: 2009, 191(10);3273-81
[PubMed:19286808]
[WorldCat.org]
[DOI]
(I p)
