Difference between revisions of "ValS"
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|style="background:#ABCDEF;" align="center"|'''Function''' || [[translation]] | |style="background:#ABCDEF;" align="center"|'''Function''' || [[translation]] | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU28090 valS] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/tRNA_charging.html tRNA charging], [http://subtiwiki.uni-goettingen.de/pathways/folate_biosynthesis.html Folate]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/tRNA_charging.html tRNA charging], [http://subtiwiki.uni-goettingen.de/pathways/folate_biosynthesis.html Folate]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[folC]]'', ''[[yszA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[folC]]'', ''[[yszA]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU28090 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU28090 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU28090 Advanced_DNA] |
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Revision as of 13:29, 13 May 2013
- Description: valyl-tRNA synthetase
| Gene name | valS |
| Synonyms | |
| Essential | yes PubMed |
| Product | valyl-tRNA synthetase |
| Function | translation |
| Gene expression levels in SubtiExpress: valS | |
| Metabolic function and regulation of this protein in SubtiPathways: tRNA charging, Folate | |
| MW, pI | 101 kDa, 4.868 |
| Gene length, protein length | 2640 bp, 880 aa |
| Immediate neighbours | folC, yszA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28090
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val) (according to Swiss-Prot)
- Protein family: ValS type 1 subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: Q05873
- KEGG entry: [3]
- E.C. number: 6.1.1.9
Additional information
Expression and regulation
- Regulatory mechanism:
- T-box: riboswitch, transcription termination/antitermination PubMed
- Additional information:
- translation is likely to require Efp due to the presence of several consecutive proline residues PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications
D Luo, J Leautey, M Grunberg-Manago, H Putzer
Structure and regulation of expression of the Bacillus subtilis valyl-tRNA synthetase gene.
J Bacteriol: 1997, 179(8);2472-8
[PubMed:9098041]
[WorldCat.org]
[DOI]
(P p)
