Difference between revisions of "BofC"
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of processing of pro-[[SigK]] by [[SpoIVFB]] | |style="background:#ABCDEF;" align="center"|'''Function''' || control of processing of pro-[[SigK]] by [[SpoIVFB]] | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27750 bofC] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/BofC BofC] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/BofC BofC] | ||
| Line 24: | Line 24: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ruvA]]'', ''[[csbX]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ruvA]]'', ''[[csbX]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27750 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27750 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27750 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:bofC_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:bofC_context.gif]] | ||
Revision as of 13:27, 13 May 2013
| Gene name | bofC |
| Synonyms | |
| Essential | no |
| Product | forespore regulator of the sigma-K checkpoint |
| Function | control of processing of pro-SigK by SpoIVFB |
| Gene expression levels in SubtiExpress: bofC | |
| Interactions involving this protein in SubtInteract: BofC | |
| MW, pI | 19 kDa, 5.753 |
| Gene length, protein length | 510 bp, 170 aa |
| Immediate neighbours | ruvA, csbX |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
sigma factors and their control, sporulation proteins, general stress proteins (controlled by SigB)
This gene is a member of the following regulons
SigB regulon, SigF regulon, SigG regulon
The gene
Basic information
- Locus tag: BSU27750
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 2BW2
- UniProt: O05391
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325]
[WorldCat.org]
[DOI]
(P p)
Hayley M Patterson, James A Brannigan, Simon M Cutting, Keith S Wilson, Anthony J Wilkinson, Eiso Ab, Tammo Diercks, Rob N de Jong, Vincent Truffault, Gert E Folkers, Robert Kaptein
The structure of bypass of forespore C, an intercompartmental signaling factor during sporulation in Bacillus.
J Biol Chem: 2005, 280(43);36214-20
[PubMed:16049010]
[WorldCat.org]
[DOI]
(P p)
A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224]
[WorldCat.org]
[DOI]
(P p)
P Wakeley, N T Hoa, S Cutting
BofC negatively regulates SpoIVB-mediated signalling in the Bacillus subtilis sigmaK-checkpoint.
Mol Microbiol: 2000, 36(6);1415-24
[PubMed:10931291]
[WorldCat.org]
[DOI]
(P p)
M Gomez, S M Cutting
Identification of a new sigmaB-controlled gene, csbX, in Bacillus subtilis.
Gene: 1997, 188(1);29-33
[PubMed:9099855]
[WorldCat.org]
[DOI]
(P p)
Manuel Gomez, Simon M Cutting
BofC encodes a putative forespore regulator of the Bacillus subtilis sigma K checkpoint.
Microbiology (Reading): 1997, 143 ( Pt 1);157-170
[PubMed:9025289]
[WorldCat.org]
[DOI]
(P p)
