Difference between revisions of "MleN"
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|style="background:#ABCDEF;" align="center"|'''Function''' || malate uptake | |style="background:#ABCDEF;" align="center"|'''Function''' || malate uptake | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU23560 mleN] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mleA]]'', ''[[ansB]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mleA]]'', ''[[ansB]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU23560 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU23560 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU23560 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:mleN_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:mleN_context.gif]] | ||
Revision as of 13:13, 13 May 2013
- Description: malate-H+/Na+-lactate antiporter
| Gene name | mleN |
| Synonyms | yqkI |
| Essential | no |
| Product | malate-H+/Na+-lactate antiporter |
| Function | malate uptake |
| Gene expression levels in SubtiExpress: mleN | |
| Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
| MW, pI | 50 kDa, 7.249 |
| Gene length, protein length | 1404 bp, 468 aa |
| Immediate neighbours | mleA, ansB |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
transporters/ other, utilization of specific carbon sources, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU23560
Phenotypes of a mutant
abrupt arrest in the mid-logarithmic phase of growth on malate when low concentrations of protonophore were present PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: nhaC Na(+)/H(+) antiporter family (according to Swiss-Prot)
- Paralogous protein(s): NhaC
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- membrane associated PubMed
Database entries
- Structure:
- UniProt: P54571
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:GP1460 (mleN::spc), available in Stülke lab
- Expression vector:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
