Difference between revisions of "Rtp"
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|style="background:#ABCDEF;" align="center"|'''Function''' || replication termination | |style="background:#ABCDEF;" align="center"|'''Function''' || replication termination | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU18490 rtp] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 14 kDa, 9.778 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 14 kDa, 9.778 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[proH]]'', ''[[yoxD]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[proH]]'', ''[[yoxD]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU18490 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU18490 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU18490 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:rtp_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:rtp_context.gif]] | ||
Revision as of 12:58, 13 May 2013
- Description: replication terminator protein
| Gene name | rtp |
| Synonyms | |
| Essential | no |
| Product | replication terminator protein |
| Function | replication termination |
| Gene expression levels in SubtiExpress: rtp | |
| MW, pI | 14 kDa, 9.778 |
| Gene length, protein length | 366 bp, 122 aa |
| Immediate neighbours | proH, yoxD |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU18490
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: pyrroline-5-carboxylate reductase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: P68732
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Qiaojuan Shi, Jose C Huguet-Tapia, Joseph E Peters
Tn917 targets the region where DNA replication terminates in Bacillus subtilis, highlighting a difference in chromosome processing in the firmicutes.
J Bacteriol: 2009, 191(24);7623-7
[PubMed:19820088]
[WorldCat.org]
[DOI]
(I p)
S Autret, A Levine, F Vannier, Y Fujita, S J Séror
The replication checkpoint control in Bacillus subtilis: identification of a novel RTP-binding sequence essential for the replication fork arrest after induction of the stringent response.
Mol Microbiol: 1999, 31(6);1665-79
[PubMed:10209741]
[WorldCat.org]
[DOI]
(P p)
A Levine, S Autret, S J Séror
A checkpoint involving RTP, the replication terminator protein, arrests replication downstream of the origin during the Stringent Response in Bacillus subtilis.
Mol Microbiol: 1995, 15(2);287-95
[PubMed:7746150]
[WorldCat.org]
[DOI]
(P p)
D B Langley, M T Smith, P J Lewis, R G Wake
Protein-nucleoside contacts in the interaction between the replication terminator protein of Bacillus subtilis and the DNA terminator.
Mol Microbiol: 1993, 10(4);771-9
[PubMed:7934839]
[WorldCat.org]
[DOI]
(P p)
P J Lewis, R G Wake
Termination of chromosome replication in Bacillus subtilis.
Res Microbiol: 1991, 142(7-8);893-900
[PubMed:1784827]
[WorldCat.org]
[DOI]
(P p)
P J Lewis, G B Ralston, R I Christopherson, R G Wake
Identification of the replication terminator protein binding sites in the terminus region of the Bacillus subtilis chromosome and stoichiometry of the binding.
J Mol Biol: 1990, 214(1);73-84
[PubMed:2115089]
[WorldCat.org]
[DOI]
(P p)
P J Lewis, M T Smith, R G Wake
A protein involved in termination of chromosome replication in Bacillus subtilis binds specifically to the terC site.
J Bacteriol: 1989, 171(6);3564-7
[PubMed:2498294]
[WorldCat.org]
[DOI]
(P p)
