Difference between revisions of "DefA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || translation | |style="background:#ABCDEF;" align="center"|'''Function''' || translation | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15720 def] |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 4.731 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 4.731 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[priA]]'', ''[[fmt]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[priA]]'', ''[[fmt]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15720 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15720 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15720 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:def_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:def_context.gif]] | ||
Revision as of 12:47, 13 May 2013
- Description: formylmethionine deformylase
| Gene name | def |
| Synonyms | yloK |
| Essential | no |
| Product | formylmethionine deformylase |
| Function | translation |
| Gene expression levels in SubtiExpress: def | |
| MW, pI | 17 kDa, 4.731 |
| Gene length, protein length | 480 bp, 160 aa |
| Immediate neighbours | priA, fmt |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
translation, protein modification
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU15720
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Formyl-L-methionyl peptide + H2O = formate + methionyl peptide (according to Swiss-Prot)
- Protein family: polypeptide deformylase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P94462
- KEGG entry: [2]
- E.C. number: 3.5.1.88
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
Julia Elisabeth Bandow, Dörte Becher, Knut Büttner, Falko Hochgräfe, Christoph Freiberg, Heike Brötz, Michael Hecker
The role of peptide deformylase in protein biosynthesis: a proteomic study.
Proteomics: 2003, 3(3);299-306
[PubMed:12627383]
[WorldCat.org]
[DOI]
(P p)
Michael Haas, Dieter Beyer, Reinhold Gahlmann, Christoph Freiberg
YkrB is the main peptide deformylase in Bacillus subtilis, a eubacterium containing two functional peptide deformylases.
Microbiology (Reading): 2001, 147(Pt 7);1783-1791
[PubMed:11429456]
[WorldCat.org]
[DOI]
(P p)
