Difference between revisions of "MhqA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || resistence to methyl-hydroxyquinone
 
|style="background:#ABCDEF;" align="center"|'''Function''' || resistence to methyl-hydroxyquinone
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU12870 mhqA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU12870 mhqA]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 35 kDa, 5.404   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 35 kDa, 5.404   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[steT]]'', ''[[ykcB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[steT]]'', ''[[ykcB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13144&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU12870 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU12870 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU12870 Advanced_DNA]
 
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Revision as of 12:37, 13 May 2013

  • Description: hydroquinone-specific dioxygenase, confers resistence to methyl-hydroxyquinone

Gene name mhqA
Synonyms ykcA
Essential no
Product hydroquinone-specific dioxygenase
Function resistence to methyl-hydroxyquinone
Gene expression levels in SubtiExpress: mhqA
MW, pI 35 kDa, 5.404
Gene length, protein length 948 bp, 316 aa
Immediate neighbours steT, ykcB
Sequences Protein DNA Advanced_DNA
Genetic context
YkcA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MhqA expression.png
























Categories containing this gene/protein

resistance against oxidative and electrophile stress

This gene is a member of the following regulons

MhqR regulon

The gene

Basic information

  • Locus tag: BSU12870

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: extradiol ring-cleavage dioxygenase family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3OAJ (MhqO, 34% identical residues)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • induced by catechol and 2-methylhydroquinone (MhqR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References