Difference between revisions of "UxaB"

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|style="background:#ABCDEF;" align="center"|'''Function''' || hexuronate utilization  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || hexuronate utilization  
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU12380 uxaB]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU12380 uxaB]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 55 kDa, 5.056   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 55 kDa, 5.056   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[exuR]]'', ''[[uxaA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[exuR]]'', ''[[uxaA]]''
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13095&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU12380 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU12380 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU12380 Advanced_DNA]
 
|-
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:uxaB_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:uxaB_context.gif]]

Revision as of 12:35, 13 May 2013

  • Description: tagaturonate reductase

Gene name uxaB
Synonyms yjmI
Essential no
Product tagaturonate reductase
Function hexuronate utilization
Gene expression levels in SubtiExpress: uxaB
MW, pI 55 kDa, 5.056
Gene length, protein length 1440 bp, 480 aa
Immediate neighbours exuR, uxaA
Sequences Protein DNA Advanced_DNA
Genetic context
UxaB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
UxaB expression.png
























Categories containing this gene/protein

utilization of specific carbon sources, sporulation proteins

This gene is a member of the following regulons

CcpA regulon, ExuR regulon, SigE regulon

The gene

Basic information

  • Locus tag: BSU12380

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-altronate + NAD+ = D-tagaturonate + NADH (according to Swiss-Prot)
  • Protein family: UxaB subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Y Miwa, A Nakata, A Ogiwara, M Yamamoto, Y Fujita
Evaluation and characterization of catabolite-responsive elements (cre) of Bacillus subtilis.
Nucleic Acids Res: 2000, 28(5);1206-10
[PubMed:10666464] [WorldCat.org] [DOI] (I p)

K R Mekjian, E M Bryan, B W Beall, C P Moran
Regulation of hexuronate utilization in Bacillus subtilis.
J Bacteriol: 1999, 181(2);426-33
[PubMed:9882655] [WorldCat.org] [DOI] (P p)

Carlo Rivolta, Blazenka Soldo, Vladimir Lazarevic, Bernard Joris, Catherine Mauël, Dimitri Karamat
A 35.7 kb DNA fragment from the Bacillus subtilis chromosome containing a putative 12.3 kb operon involved in hexuronate catabolism and a perfectly symmetrical hypothetical catabolite-responsive element.
Microbiology (Reading): 1998, 144 ( Pt 4);877-884
[PubMed:9579062] [WorldCat.org] [DOI] (P p)