Difference between revisions of "PhoA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || aquisition of phosphate upon phosphoate starvation  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || aquisition of phosphate upon phosphoate starvation  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU09410 phoA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU09410 phoA]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 50 kDa, 9.926   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 50 kDa, 9.926   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoVR]]'', ''[[lytE]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoVR]]'', ''[[lytE]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12780&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU09410 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU09410 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU09410 Advanced_DNA]
 
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Revision as of 12:26, 13 May 2013

  • Description: alkaline phosphatase A

Gene name phoA
Synonyms phoAIV
Essential no
Product alkaline phosphatase A
Function aquisition of phosphate upon phosphoate starvation
Gene expression levels in SubtiExpress: phoA
MW, pI 50 kDa, 9.926
Gene length, protein length 1383 bp, 461 aa
Immediate neighbours spoVR, lytE
Sequences Protein DNA Advanced_DNA
Genetic context
PhoA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PhoA expression.png
























Categories containing this gene/protein

phosphate metabolism

This gene is a member of the following regulons

PhoP regulon

The gene

Basic information

  • Locus tag: BSU09410

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: A phosphate monoester + H2O = an alcohol + phosphate (according to Swiss-Prot)
  • Protein family: alkaline phosphatase family (according to Swiss-Prot)
  • Paralogous protein(s): PhoB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions of phosphate limitation (PhoP) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Marion Hulett, University of Illinois at Chicago, USA Homepage

Your additional remarks

References