Difference between revisions of "NatR"
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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of the ''[[natA]]-[[natB]]'' operon | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of the ''[[natA]]-[[natB]]'' operon | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02740 natR] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/NatR NatR] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/NatR NatR] | ||
| Line 24: | Line 24: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[natK]]'', ''[[natA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[natK]]'', ''[[natA]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02740 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02740 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02740 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yccH_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yccH_context.gif]] | ||
Revision as of 12:04, 13 May 2013
- Description: two-component response regulator, regulation of the natA-natB operon
| Gene name | natR |
| Synonyms | yccH |
| Essential | no |
| Product | two-component response regulator |
| Function | regulation of the natA-natB operon |
| Gene expression levels in SubtiExpress: natR | |
| Interactions involving this protein in SubtInteract: NatR | |
| MW, pI | 26 kDa, 6.614 |
| Gene length, protein length | 699 bp, 233 aa |
| Immediate neighbours | natK, natA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
metal ion homeostasis (K, Na, Ca, Mg), transcription factors and their control, phosphoproteins
This gene is a member of the following regulons
The NatR regulon:
The gene
Basic information
- Locus tag: BSU02740
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: OmpR family of two-component response regulators
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylated by NatK on an Asp residue
- Cofactor(s):
- Effectors of protein activity: phosphorylation likely affects DNA-binding activity
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P70955
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: natR (according to DBTBS)
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Mitsuo Ogura, Kensuke Tsukahara, Kentaro Hayashi, Teruo Tanaka
The Bacillus subtilis NatK-NatR two-component system regulates expression of the natAB operon encoding an ABC transporter for sodium ion extrusion.
Microbiology (Reading): 2007, 153(Pt 3);667-675
[PubMed:17322186]
[WorldCat.org]
[DOI]
(P p)
C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672]
[WorldCat.org]
[DOI]
(P p)
