Difference between revisions of "HolA"
| Line 90: | Line 90: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''[[SubtInteract|Interactions]]:''' | + | * '''[[SubtInteract|Interactions]]:'''# |
| + | ** [[DnaX]](3)-[[HolA]]-[[HolB]], the clamp-loader complex {{PubMed|23525462}} | ||
** part of the [[replisome]]: [[PolC]]-[[HolA]]-[[HolB]]-[[DnaX]]-[[DnaN]]-[[DnaG]]-[[DnaC]]-[[DnaI]]-[[DnaD]]-[[SsbA]]-[[DnaE]]-[[PriA]]-[[DnaB]] {{PubMed|20122408}} | ** part of the [[replisome]]: [[PolC]]-[[HolA]]-[[HolB]]-[[DnaX]]-[[DnaN]]-[[DnaG]]-[[DnaC]]-[[DnaI]]-[[DnaD]]-[[SsbA]]-[[DnaE]]-[[PriA]]-[[DnaB]] {{PubMed|20122408}} | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=holA_2636096_2637139_-1 holA] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=holA_2636096_2637139_-1 holA] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
* '''Regulation:''' | * '''Regulation:''' | ||
| Line 140: | Line 141: | ||
=References= | =References= | ||
| − | + | <pubmed>16479537 20122408 23525462 23268446</pubmed> | |
| − | <pubmed>16479537 20122408 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 18:16, 27 March 2013
- Description: DNA polymerase III, delta subunit, part of the replisome
| Gene name | holA |
| Synonyms | yqeN |
| Essential | yes PubMed |
| Product | DNA polymerase III, delta subunit |
| Function | DNA replication |
| Gene expression levels in SubtiExpress: holA | |
| Interactions involving this protein in SubtInteract: HolA | |
| MW, pI | 40 kDa, 6.231 |
| Gene length, protein length | 1041 bp, 347 aa |
| Immediate neighbours | rpsT, yqzM |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
DNA replication, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU25560
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- required for bacteriophage SPP1 replication PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: Nucleoid (Mid-cell) PubMed
Database entries
- Structure:
- UniProt: P54459
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
