Difference between revisions of "SigY"
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|style="background:#ABCDEF;" align="center"| '''Product''' || [[RNA polymerase]] ECF-type [[sigma factor]] SigY | |style="background:#ABCDEF;" align="center"| '''Product''' || [[RNA polymerase]] ECF-type [[sigma factor]] SigY | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || [[ | + | |style="background:#ABCDEF;" align="center"|'''Function''' || maintenance of the [[SPß prophage]] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU38700 sigY] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU38700 sigY] | ||
| Line 54: | Line 54: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * loss of the [[SPß prophage]] {{PubMed|22400495}} | ||
| + | * sensitive to killing by [[SunA|sublancin]] {{PubMed|22400495}} | ||
| + | * no production of [[SunA|sublancin]] {{PubMed|22400495}} | ||
=== Database entries === | === Database entries === | ||
Revision as of 16:21, 10 January 2013
- Description: RNA polymerase ECF-type sigma factor SigY
| Gene name | sigY |
| Synonyms | yxlB |
| Essential | no |
| Product | RNA polymerase ECF-type sigma factor SigY |
| Function | maintenance of the SPß prophage |
| Gene expression levels in SubtiExpress: sigY | |
| Interactions involving this protein in SubtInteract: SigY | |
| MW, pI | 21 kDa, 9.549 |
| Gene length, protein length | 534 bp, 178 aa |
| Immediate neighbours | yxlC, yxlA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transcription, sigma factors and their control, cell envelope stress proteins (controlled by SigM, V, W, X, Y)
This gene is a member of the following regulons
The SigY regulon
The gene
Basic information
- Locus tag: BSU38700
Phenotypes of a mutant
- loss of the SPß prophage PubMed
- sensitive to killing by sublancin PubMed
- no production of sublancin PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ECF subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P94370
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
The SigY regulon
Thorsten Mascher, Anna-Barbara Hachmann, John D Helmann
Regulatory overlap and functional redundancy among Bacillus subtilis extracytoplasmic function sigma factors.
J Bacteriol: 2007, 189(19);6919-27
[PubMed:17675383]
[WorldCat.org]
[DOI]
(P p)
Other original publications
Additional publications: PubMed
Mika Yoshimura, Kei Asai, Yoshito Sadaie, Hirofumi Yoshikawa
Interaction of Bacillus subtilis extracytoplasmic function (ECF) sigma factors with the N-terminal regions of their potential anti-sigma factors.
Microbiology (Reading): 2004, 150(Pt 3);591-599
[PubMed:14993308]
[WorldCat.org]
[DOI]
(P p)
Shigeo Tojo, Masayuki Matsunaga, Takashi Matsumoto, Choong-Min Kang, Hirotake Yamaguchi, Kei Asai, Yoshito Sadaie, Ken-ichi Yoshida, Yasutaro Fujita
Organization and expression of the Bacillus subtilis sigY operon.
J Biochem: 2003, 134(6);935-46
[PubMed:14769884]
[WorldCat.org]
[DOI]
(P p)
