YfiY

• Description: ABC transporter for the siderophore schizokinen and arthrobactin (binding protein), works with ATPase YusV
  
  

Gene name	yfiY
Synonyms
Essential	no
Product	ABC transporter for the siderophore schizokinen and arthrobactin (binding protein)
Function	acquisition of iron
Gene expression levels in SubtiExpress: yfiY
Interactions involving this protein in SubtInteract: YfiY
MW, pI	36 kDa, 7.173
Gene length, protein length	975 bp, 325 aa
Immediate neighbours	mprF, yfiZ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, acquisition of iron, iron metabolism, membrane proteins, phosphoproteins

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

• Locus tag: BSU08440

Phenotypes of a mutant

• poor growth with the xenosiderophores arthrobactin or aerobactin as single source of iron PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: Fe/B12 periplasmic-binding domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylation on (Ser-290 OR Thr-302) PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YusV-(YfhA-YfiZ)-YfiY PubMed

• Localization:
  • associated to the membrane (via YfhA-YfiZ) PubMed
  • extracellular (signal peptide) PubMed

Database entries

• Structure:

• UniProt: O31567

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yfiY

• Expression browser: yfiY PubMed

• Sigma factor:

• Regulation:
  • repressed unless the cells enter an iron starvation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: