Difference between revisions of "YneA"

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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yneA_1918406_1918723_1 yneA] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yneA_1918406_1918723_1 yneA] {{PubMed|22383849}}
  
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Revision as of 19:48, 15 December 2012

  • Description: inhibits cell division during SOS response

Gene name yneA
Synonyms
Essential no
Product cell division control protein
Function inhibits cell division during SOS response
Gene expression levels in SubtiExpress: yneA
MW, pI 11 kDa, 4.613
Gene length, protein length 315 bp, 105 aa
Immediate neighbours lexA, yneB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YneA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YneA expression.png















Categories containing this gene/protein

cell division

This gene is a member of the following regulons

LexA regulon

The gene

Basic information

  • Locus tag: BSU17860

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: yneA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
    • LysM peptidoglycan binding domain PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:
    • YneA is rapidly degraded by extracellular proteases PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Allison H Mo, William F Burkholder
YneA, an SOS-induced inhibitor of cell division in Bacillus subtilis, is regulated posttranslationally and requires the transmembrane region for activity.
J Bacteriol: 2010, 192(12);3159-73
[PubMed:20400548] [WorldCat.org] [DOI] (I p)

Nora Au, Elke Kuester-Schoeck, Veena Mandava, Laura E Bothwell, Susan P Canny, Karen Chachu, Sierra A Colavito, Shakierah N Fuller, Eli S Groban, Laura A Hensley, Theresa C O'Brien, Amish Shah, Jessica T Tierney, Louise L Tomm, Thomas M O'Gara, Alexi I Goranov, Alan D Grossman, Charles M Lovett
Genetic composition of the Bacillus subtilis SOS system.
J Bacteriol: 2005, 187(22);7655-66
[PubMed:16267290] [WorldCat.org] [DOI] (P p)

Yoshikazu Kawai, Shigeki Moriya, Naotake Ogasawara
Identification of a protein, YneA, responsible for cell division suppression during the SOS response in Bacillus subtilis.
Mol Microbiol: 2003, 47(4);1113-22
[PubMed:12581363] [WorldCat.org] [DOI] (P p)