Difference between revisions of "SunI"
| Line 8: | Line 8: | ||
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yolF '' | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yolF '' | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Essential''' || | + | |style="background:#ABCDEF;" align="center"| '''Essential''' || yes {{PubMed|19047653}} |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || bacteriocin producer immunity protein | |style="background:#ABCDEF;" align="center"| '''Product''' || bacteriocin producer immunity protein | ||
| Line 41: | Line 41: | ||
{{SubtiWiki category|[[toxins, antitoxins and immunity against toxins]]}}, | {{SubtiWiki category|[[toxins, antitoxins and immunity against toxins]]}}, | ||
{{SubtiWiki category|[[SP-beta prophage]]}}, | {{SubtiWiki category|[[SP-beta prophage]]}}, | ||
| − | {{SubtiWiki category|[[membrane proteins]]}} | + | {{SubtiWiki category|[[membrane proteins]]}}, |
| + | {{SubtiWiki category|[[essential genes]]}} | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| Line 53: | Line 54: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * essential {{PubMed|19047653}} | ||
=== Database entries === | === Database entries === | ||
Revision as of 12:45, 5 December 2012
- Description: bacteriocin producer immunity protein
| Gene name | sunI |
| Synonyms | yolF |
| Essential | yes PubMed |
| Product | bacteriocin producer immunity protein |
| Function | immunity to sublancin |
| Gene expression levels in SubtiExpress: sunI | |
| MW, pI | 12 kDa, 9.222 |
| Gene length, protein length | 315 bp, 105 aa |
| Immediate neighbours | sunA, uvrX |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
resistance against toxins/ antibiotics, toxins, antitoxins and immunity against toxins, SP-beta prophage, membrane proteins, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU21490
Phenotypes of a mutant
- essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: mediates immunity to sublancin PubMed
- Protein family: ribosomal protein S1P family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31989
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Jan Maarten van Dijl, Groningen, Netherlands
Your additional remarks
References
Pierre Nicolas, Ulrike Mäder, Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, Mark Hoebeke, Stéphane Aymerich, Dörte Becher, Paola Bisicchia, Eric Botella, Olivier Delumeau, Geoff Doherty, Emma L Denham, Mark J Fogg, Vincent Fromion, Anne Goelzer, Annette Hansen, Elisabeth Härtig, Colin R Harwood, Georg Homuth, Hanne Jarmer, Matthieu Jules, Edda Klipp, Ludovic Le Chat, François Lecointe, Peter Lewis, Wolfram Liebermeister, Anika March, Ruben A T Mars, Priyanka Nannapaneni, David Noone, Susanne Pohl, Bernd Rinn, Frank Rügheimer, Praveen K Sappa, Franck Samson, Marc Schaffer, Benno Schwikowski, Leif Steil, Jörg Stülke, Thomas Wiegert, Kevin M Devine, Anthony J Wilkinson, Jan Maarten van Dijl, Michael Hecker, Uwe Völker, Philippe Bessières, Philippe Noirot
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Science: 2012, 335(6072);1103-6
[PubMed:22383849]
[WorldCat.org]
[DOI]
(I p)
Jean-Yves F Dubois, Thijs R H M Kouwen, Anna K C Schurich, Carlos R Reis, Hendrik T Ensing, Erik N Trip, Jessica C Zweers, Jan Maarten van Dijl
Immunity to the bacteriocin sublancin 168 Is determined by the SunI (YolF) protein of Bacillus subtilis.
Antimicrob Agents Chemother: 2009, 53(2);651-61
[PubMed:19047653]
[WorldCat.org]
[DOI]
(I p)
Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711]
[WorldCat.org]
[DOI]
(I p)
