Pmi

• Description: mannose-6-phosphate isomerase
  
  

Gene name	pmi
Synonyms	yvyI
Essential	no
Product	mannose-6-phosphate isomerase
Function	mannose utilization
Gene expression levels in SubtiExpress: pmi
MW, pI	35 kDa, 4.982
Gene length, protein length	948 bp, 316 aa
Immediate neighbours	lytD, gerBA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources

The gene

Basic information

• Locus tag: BSU35790

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: D-mannose 6-phosphate = D-fructose 6-phosphate (according to Swiss-Prot)

• Protein family: mannose-6-phosphate isomerase type 1 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1QWR

• UniProt: P39841

• KEGG entry: [3]

• E.C. number: 5.3.1.8

Expression and regulation

• Operon: pmi PubMed

• Expression browser: pmi PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Soo-Jin Yeom, Yeong-Su Kim, Deok-Kun Oh
Development of novel sugar isomerases by optimization of active sites in phosphosugar isomerases for monosaccharides.
Appl Environ Microbiol: 2013, 79(3);982-8
[PubMed:23204422] [WorldCat.org] [DOI] (I p)

P Margot, C Mauël, D Karamata
The gene of the N-acetylglucosaminidase, a Bacillus subtilis 168 cell wall hydrolase not involved in vegetative cell autolysis.
Mol Microbiol: 1994, 12(4);535-45
[PubMed:7934877] [WorldCat.org] [DOI] (P p)