TcyA

• Description: cystine ABC transporter (binding protein)
  
  

Gene name	tcyA
Synonyms	yckK
Essential	no
Product	cystine ABC transporter (binding protein)
Function	cystine uptake
Gene expression levels in SubtiExpress: tcyA
Interactions involving this protein in SubtInteract: TcyA
MW, pI	29 kDa, 9.118
Gene length, protein length	804 bp, 268 aa
Immediate neighbours	tcyB, bsdA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, biosynthesis/ acquisition of amino acids, membrane proteins

The gene

Basic information

• Locus tag: BSU03610

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: bacterial solute-binding protein 3 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • TcyC-TcyB-TcyA PubMed

• Localization:
  • attached to the membrane via TcyB PubMed

Database entries

• Structure:

• UniProt: P42199

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: tcyA-tcyB-tcyC (putative) PubMed

• Expression browser: tcyA PubMed

• Sigma factor:

• Regulation:
  • very weakly expressed under all conditions PubMed
  • strongly repressed in response to glucose starvation in M9 medium PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed