YfmF

Gene name	yfmF
Synonyms
Essential	no
Product	iron/citrate ABC transporter (ATP-binding protein)
Function	iron uptake
Gene expression levels in SubtiExpress: yfmF
Interactions involving this protein in SubtInteract: YfmF
MW, pI	29 kDa, 6.07
Gene length, protein length	798 bp, 266 aa
Immediate neighbours	yfmG, yfmE
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

• Locus tag: BSU07490

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transporter domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YfmF-(YfmD-YfmE)-(YfmC-YhfQ) PubMed

• Localization:
  • associated to the membrane (via YfmD-YfmE) PubMed

Database entries

• Structure:

• UniProt: O34510

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yfmC-yfmD-yfmE-yfmF PubMed

• Expression browser: yfmF PubMed

• Sigma factor:

• Regulation:
  • induced upon iron starvation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Juliane Ollinger, Kyung-Bok Song, Haike Antelmann, Michael Hecker, John D Helmann
Role of the Fur regulon in iron transport in Bacillus subtilis.
J Bacteriol: 2006, 188(10);3664-73
[PubMed:16672620] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)