Difference between revisions of "YbbA"

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Revision as of 08:10, 8 August 2012

  • Description: putative bacillibactin esterase

Gene name ybbA
Synonyms
Essential no
Product putative bacillibactin esterase
Function iron acquisition from bacillibactin
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 21 kDa, 7.912
Gene length, protein length 567 bp, 189 aa
Immediate neighbours ybaS, feuC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YbbA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YbbA expression.png




























Categories containing this gene/protein

acquisition of iron, iron metabolism

This gene is a member of the following regulons

Btr regulon, CitB regulon, Fur regulon

The gene

Basic information

  • Locus tag: BSU01600

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of iron (Fur, CitB) PubMed
    • induced in the presence of iron chelators bacillibactin or enterobactin (Btr) PubMed
  • Regulatory mechanism:
    • Fur: transcription repression PubMed
    • CitB: binding to the iron responsive element in the absence of iron
    • Btr: transcription activation in the presence of the co-activators bacillibactin or enterobactin PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ahmed Gaballa, John D Helmann
Substrate induction of siderophore transport in Bacillus subtilis mediated by a novel one-component regulator.
Mol Microbiol: 2007, 66(1);164-73
[PubMed:17725565] [WorldCat.org] [DOI] (P p)

Noel Baichoo, Tao Wang, Rick Ye, John D Helmann
Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon.
Mol Microbiol: 2002, 45(6);1613-29
[PubMed:12354229] [WorldCat.org] [DOI] (P p)