Difference between revisions of "MntH"
m (Reverted edits by 134.76.70.252 (talk) to last revision by Umaeder) |
|||
| Line 1: | Line 1: | ||
| − | + | * '''Description:''' manganese transporter (proton symport) <br/><br/> | |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 13: | Line 13: | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || manganese uptake | |style="background:#ABCDEF;" align="center"|'''Function''' || manganese uptake | ||
| − | |||
| − | |||
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]''' | ||
| Line 28: | Line 26: | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:mntH_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:mntH_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
| − | |||
| − | |||
|- | |- | ||
|} | |} | ||
__TOC__ | __TOC__ | ||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
<br/><br/><br/><br/><br/><br/> | <br/><br/><br/><br/><br/><br/> | ||
| Line 112: | Line 102: | ||
* '''Operon:''' ''mntH'' [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed] | * '''Operon:''' ''mntH'' [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed] | ||
| − | * | + | * '''[[Sigma factor]]:''' |
| − | |||
| − | |||
* '''Regulation:''' repressed by Mn(2+) ([[MntR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed] | * '''Regulation:''' repressed by Mn(2+) ([[MntR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed] | ||
| Line 122: | Line 110: | ||
** [[MntR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed] | ** [[MntR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10760146 PubMed] | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 11:30, 7 August 2012
- Description: manganese transporter (proton symport)
| Gene name | mntH |
| Synonyms | ydaR |
| Essential | no |
| Product | manganese transporter (proton symport)) |
| Function | manganese uptake |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 45 kDa, 9.889 |
| Gene length, protein length | 1275 bp, 425 aa |
| Immediate neighbours | ydzK, ydaS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
transporters/ other, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU04360
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: NRAMP family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P96593
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: mntH PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
John Helmann, Cornell University, USA Homepage
Your additional remarks
References
Emmanuel Guedon, Charles M Moore, Qiang Que, Tao Wang, Rick W Ye, John D Helmann
The global transcriptional response of Bacillus subtilis to manganese involves the MntR, Fur, TnrA and sigmaB regulons.
Mol Microbiol: 2003, 49(6);1477-91
[PubMed:12950915]
[WorldCat.org]
[DOI]
(P p)
Q Que, J D Helmann
Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins.
Mol Microbiol: 2000, 35(6);1454-68
[PubMed:10760146]
[WorldCat.org]
[DOI]
(P p)
