Difference between revisions of "RapC"
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| − | + | * '''Description:''' [[response regulator aspartate phosphatase]], controls [[ComA]] activity <br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[ComA]] activity | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[ComA]] activity | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/RapC RapC] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/RapC RapC] | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:rapC_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:rapC_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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__TOC__ | __TOC__ | ||
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<br/><br/> | <br/><br/> | ||
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* '''Operon:''' ''[[rapC]]-[[phrC]]'' {{PubMed|10464187}} | * '''Operon:''' ''[[rapC]]-[[phrC]]'' {{PubMed|10464187}} | ||
| − | * | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|10464187}} |
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* '''Regulation:''' | * '''Regulation:''' | ||
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** [[CodY]]: transcription repression {{PubMed|10464187}} | ** [[CodY]]: transcription repression {{PubMed|10464187}} | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 11:19, 7 August 2012
- Description: response regulator aspartate phosphatase, controls ComA activity
| Gene name | rapC |
| Synonyms | yclL |
| Essential | no |
| Product | response regulator aspartate phosphatase |
| Function | control of ComA activity |
| Interactions involving this protein in SubtInteract: RapC | |
| MW, pI | 45 kDa, 5.024 |
| Gene length, protein length | 1146 bp, 382 aa |
| Immediate neighbours | yclK, phrC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
genetic competence, protein modification, transcription factors and their control, quorum sensing
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU03770
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: RAP family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
Database entries
- Structure:
- UniProt: P94415
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Natalia Comella, Alan D Grossman
Conservation of genes and processes controlled by the quorum response in bacteria: characterization of genes controlled by the quorum-sensing transcription factor ComA in Bacillus subtilis.
Mol Microbiol: 2005, 57(4);1159-74
[PubMed:16091051]
[WorldCat.org]
[DOI]
(P p)
Leighton Core, Marta Perego
TPR-mediated interaction of RapC with ComA inhibits response regulator-DNA binding for competence development in Bacillus subtilis.
Mol Microbiol: 2003, 49(6);1509-22
[PubMed:12950917]
[WorldCat.org]
[DOI]
(P p)
B A Lazazzera, I G Kurtser, R S McQuade, A D Grossman
An autoregulatory circuit affecting peptide signaling in Bacillus subtilis.
J Bacteriol: 1999, 181(17);5193-200
[PubMed:10464187]
[WorldCat.org]
[DOI]
(P p)
