RluB

• Description: pseudouridine synthase
  
  

Gene name	rluB
Synonyms	ypuL
Essential	no
Product	pseudouridine synthase
Function	23S rRNA modification
Gene expression levels in SubtiExpress: rluB
MW, pI	25 kDa, 10.253
Gene length, protein length	687 bp, 229 aa
Immediate neighbours	resA, spmB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed 500px

Categories containing this gene/protein

translation, membrane proteins

The gene

Basic information

• Locus tag: BSU23160

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: rRNA uridine = rRNA pseudouridine (according to Swiss-Prot)

• Protein family: pseudouridine synthase rsuA family (according to Swiss-Prot)

• Paralogous protein(s): YtzF

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P35159

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: rluB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

L Niu, B G Lane, J Ofengand
Cloning and characterization of the 23S RNA pseudouridine 2633 synthase from Bacillus subtilis.
Biochemistry: 1999, 38(2);629-35
[PubMed:9888802] [WorldCat.org] [DOI] (P p)