Difference between revisions of "Ndk"
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|style="background:#ABCDEF;" align="center"|'''Function''' || maintainance of an equilibrium between the <br/>concentrations of different nucleoside triphosphates | |style="background:#ABCDEF;" align="center"|'''Function''' || maintainance of an equilibrium between the <br/>concentrations of different nucleoside triphosphates | ||
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| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU22730 ndk] | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/pyrimidines_metabolism.html Pyrimidines], [http://subtiwiki.uni-goettingen.de/pathways/purines_salvage_pathways.html Purine salvage]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/pyrimidines_metabolism.html Pyrimidines], [http://subtiwiki.uni-goettingen.de/pathways/purines_salvage_pathways.html Purine salvage]''' | ||
Revision as of 11:06, 7 August 2012
- Description: nucleoside diphosphate kinase
| Gene name | ndk |
| Synonyms | |
| Essential | no |
| Product | nucleoside diphosphate kinase |
| Function | maintainance of an equilibrium between the concentrations of different nucleoside triphosphates |
| Gene expression levels in SubtiExpress: ndk | |
| Metabolic function and regulation of this protein in SubtiPathways: Pyrimidines, Purine salvage | |
| MW, pI | 16 kDa, 5.568 |
| Gene length, protein length | 447 bp, 149 aa |
| Immediate neighbours | cheR, hepT |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
nucleotide metabolism/ other, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU22730
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate (according to Swiss-Prot)
- Protein family: phosphate acetyltransferase and butyryltransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation on Thr-92 AND Ser-123 PubMed
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 1WKJ (from Thermus thermophilus, 59% identity, 82% similarity)
- UniProt: P31103
- KEGG entry: [2]
- E.C. number: 2.7.4.6
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Boris Macek, Ivan Mijakovic, Jesper V Olsen, Florian Gnad, Chanchal Kumar, Peter R Jensen, Matthias Mann
The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis.
Mol Cell Proteomics: 2007, 6(4);697-707
[PubMed:17218307]
[WorldCat.org]
[DOI]
(P p)
