Difference between revisions of "MifM"
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || sensor of [[SpoIIIJ]] activity | |style="background:#ABCDEF;" align="center"| '''Product''' || sensor of [[SpoIIIJ]] activity | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of ''[[yidC2]]'' translation |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 11 kDa, 5.829 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 11 kDa, 5.829 | ||
| Line 84: | Line 84: | ||
** the C-terminus of MifM interacts with the ribosomal polypeptide exit tunnel {{PubMed|19779460}} | ** the C-terminus of MifM interacts with the ribosomal polypeptide exit tunnel {{PubMed|19779460}} | ||
| − | * '''[[Localization]]:''' membrane {{PubMed|19779460}} | + | * '''[[Localization]]:''' |
| + | ** membrane {{PubMed|19779460}} | ||
=== Database entries === | === Database entries === | ||
Revision as of 10:37, 7 August 2012
- Description: ribosome-nascent chain sensor of membrane protein biogenesis
| Gene name | mifM |
| Synonyms | yqzJ |
| Essential | no |
| Product | sensor of SpoIIIJ activity |
| Function | control of yidC2 translation |
| MW, pI | 11 kDa, 5.829 |
| Gene length, protein length | 285 bp, 95 aa |
| Immediate neighbours | polY1, yidC2 |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
translation, membrane proteins
This gene is a member of the following regulons
The MifM regulon: yqjG
The gene
Basic information
- Locus tag: BSU23880
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: acts as a kind of "leader peptide" that does or does not allow translation through a hairpin structure in the yqjG mRNA PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- the C-terminus of MifM interacts with the ribosomal polypeptide exit tunnel PubMed
- Localization:
- membrane PubMed
Database entries
- Structure:
- UniProt: Q7WY64
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
- An antisense RNA is predicted for mifM PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
