Difference between revisions of "SpoVC"
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| − | + | * '''Description:''' general stress protein, peptidyl-tRNA hydrolase <br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Function''' || spore coat formation | |style="background:#ABCDEF;" align="center"|'''Function''' || spore coat formation | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 20 kDa, 5.58 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 20 kDa, 5.58 | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:spoVC_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:spoVC_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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__TOC__ | __TOC__ | ||
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* '''Operon:''' | * '''Operon:''' | ||
| − | * | + | * '''[[Sigma factor]]:''' [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed] |
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* '''Regulation:''' induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed] | * '''Regulation:''' induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed] | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 10:16, 7 August 2012
- Description: general stress protein, peptidyl-tRNA hydrolase
| Gene name | spoVC |
| Synonyms | pth |
| Essential | yes PubMed |
| Product | peptidyl-tRNA hydrolase |
| Function | spore coat formation |
| MW, pI | 20 kDa, 5.58 |
| Gene length, protein length | 564 bp, 188 aa |
| Immediate neighbours | ctc, fin |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
translation, general stress proteins (controlled by SigB), essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00530
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA (according to Swiss-Prot)
- Protein family: PTH family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P37470
- KEGG entry: [2]
- E.C. number: 3.1.1.29
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Jeanne Menez, Richard H Buckingham, Miklos de Zamaroczy, Celine Karmazyn Campelli
Peptidyl-tRNA hydrolase in Bacillus subtilis, encoded by spoVC, is essential to vegetative growth, whereas the homologous enzyme in Saccharomyces cerevisiae is dispensable.
Mol Microbiol: 2002, 45(1);123-9
[PubMed:12100553]
[WorldCat.org]
[DOI]
(P p)
A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224]
[WorldCat.org]
[DOI]
(P p)
