MraZ

• Description: Putative DNA-binding protein
  
  

Gene name	mraZ
Synonyms	yllB
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: mraZ
MW, pI	16 kDa, 4.969
Gene length, protein length	429 bp, 143 aa
Immediate neighbours	bshC, mraW
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

proteins of unknown function

The gene

Basic information

• Locus tag: BSU15130

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Additional information

the E.coli homolog: mraZ

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: mraZ family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • nucleoid (heterogeneous) PubMed

Database entries

• Structure: 1N0G (the homolog from Mycoplasma pneumoniae) PubMed

• UniProt: P55343

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: mraZ-mraW-ftsL-pbpB PubMed

• Expression browser: mraZ PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Melanie A Adams, Christian M Udell, Gour Pada Pal, Zongchao Jia
MraZ from Escherichia coli: cloning, purification, crystallization and preliminary X-ray analysis.
Acta Crystallogr Sect F Struct Biol Cryst Commun: 2005, 61(Pt 4);378-80
[PubMed:16511046] [WorldCat.org] [DOI] (I p)

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

Shengfeng Chen, Jaru Jancrick, Hisao Yokota, Rosalind Kim, Sung-Hou Kim
Crystal structure of a protein associated with cell division from Mycoplasma pneumoniae (GI: 13508053): a novel fold with a conserved sequence motif.
Proteins: 2004, 55(4);785-91
[PubMed:15146477] [WorldCat.org] [DOI] (I p)

R A Daniel, A M Williams, J Errington
A complex four-gene operon containing essential cell division gene pbpB in Bacillus subtilis.
J Bacteriol: 1996, 178(8);2343-50
[PubMed:8636036] [WorldCat.org] [DOI] (P p)

A Yanouri, R A Daniel, J Errington, C E Buchanan
Cloning and sequencing of the cell division gene pbpB, which encodes penicillin-binding protein 2B in Bacillus subtilis.
J Bacteriol: 1993, 175(23);7604-16
[PubMed:8244929] [WorldCat.org] [DOI] (P p)