YkfC

Gene name	ykfC
Synonyms
Essential	no
Product	D-glutamyl-L-amino acid peptidase
Function	cell wall metabolism
Gene expression levels in SubtiExpress: ykfC
MW, pI	32 kDa, 6.346
Gene length, protein length	888 bp, 296 aa
Immediate neighbours	ykfB, ykfD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall/ other

This gene is a member of the following regulons

CodY regulon

The gene

Basic information

• Locus tag: BSU12990

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: cleaves L-Ala-γ-D-Glu dipeptides from cell wall peptides PubMed

• Protein family: nlpC/p60 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O35010

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ykfC PubMed

• Sigma factor:

• Regulation: repressed by CodY PubMed

• Regulatory mechanism: CodY: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Virginie Molle, Yoshiko Nakaura, Robert P Shivers, Hirotake Yamaguchi, Richard Losick, Yasutaro Fujita, Abraham L Sonenshein
Additional targets of the Bacillus subtilis global regulator CodY identified by chromatin immunoprecipitation and genome-wide transcript analysis.
J Bacteriol: 2003, 185(6);1911-22
[PubMed:12618455] [WorldCat.org] [DOI] (P p)

All publications: PubMed