Difference between revisions of "ComN"

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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' post-transcriptional control of ''[[comEA]]'' expression  [http://www.ncbi.nlm.nih.gov/sites/entrez/19028902 PubMed]
+
* '''Catalyzed reaction/ biological activity:'''  
 
+
** post-transcriptional control of ''[[comEA]]'' expression  [http://www.ncbi.nlm.nih.gov/sites/entrez/19028902 PubMed]
 +
** promotes the accumulation of its target ''[[comEA]]'' mRNA to septal and polar sites {{PubMed|22582279}}
 
* '''Protein family:'''
 
* '''Protein family:'''
  
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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
 +
** [[DivIVA]]-[[ComN]] {{PubMed|22582279}}
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
** cell membrane (according to Swiss-Prot)
+
** localizes to the division site and cell poles in a [[DivIVA]] dependent fashion {{PubMed|22582279}}
  
 
=== Database entries ===
 
=== Database entries ===
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=References=
 
=References=
  
<pubmed>19028902,,19028902, </pubmed>
+
<pubmed>19028902,22582279, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 13:50, 23 May 2012

  • Description: mediates post-transcriptional control of comE operon expression

Gene name comN
Synonyms yrzD
Essential no
Product post-transcriptional regulator of comE expression
Function regulation of competence and DNA uptake
MW, pI 11 kDa, 4.622
Gene length, protein length 294 bp, 98 aa
Immediate neighbours secDF, spoVB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YrzD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComN expression.png
























Categories containing this gene/protein

genetic competence, membrane proteins

This gene is a member of the following regulons

The ComN regulon: comEA-comEB-comEC

The gene

Basic information

  • Locus tag: BSU27660

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • post-transcriptional control of comEA expression PubMed
    • promotes the accumulation of its target comEA mRNA to septal and polar sites PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References