Difference between revisions of "KatA"

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(Categories containing this gene/protein)
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* '''Modification:'''
 
* '''Modification:'''
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** phosphorylated on Arg-366 {{PubMed|22517742}}
  
 
* '''Cofactor(s):''' contains an iron-sulfur cluster, heme
 
* '''Cofactor(s):''' contains an iron-sulfur cluster, heme
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=References=
 
=References=
  
<pubmed>9393707,7667267,,8931328,8932315,11532148, 22174384 22194458 </pubmed>
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<pubmed>9393707,7667267,,8931328,8932315,11532148, 22174384 22194458 22517742</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 14:49, 21 April 2012

  • Description: main vegetative catalase 1

Gene name katA
Synonyms kat-19
Essential no
Product vegetative catalase
Function detoxification (degradation) of hydrogen peroxide
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 54 kDa, 6.151
Gene length, protein length 1449 bp, 483 aa
Immediate neighbours senS, ssuB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
KatA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
KatA expression.png




























Categories containing this gene/protein

resistance against oxidative and electrophile stress, phosphoproteins

This gene is a member of the following regulons

PerR regulon

The gene

Basic information

  • Locus tag: BSU08820

Phenotypes of a mutant

  • increased sensitivity to oxidative stress PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 H2O2 = O2 + 2 H2O (according to Swiss-Prot)
  • Protein family: catalase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
    • phosphorylated on Arg-366 PubMed
  • Cofactor(s): contains an iron-sulfur cluster, heme
  • Effectors of protein activity:

Database entries

  • Structure: 1SI8 (enzyme from Enterococcus faecalis, 68% identity)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • induced in the presence of hydrogen peroxide and paraquat (PerR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References