Difference between revisions of "Apt"
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|colspan="2" | '''Genetic context''' <br/> [[Image:apt_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:apt_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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| + | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=apt_2822901_2823413_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:apt_expression.png|500px]] | ||
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Revision as of 09:59, 20 April 2012
- Description: adenine phosphoribosyltransferase, universally conserved protein
| Gene name | apt |
| Synonyms | |
| Essential | no |
| Product | adenine phosphoribosyltransferase |
| Function | purine salvage and interconversion |
| Metabolic function and regulation of this protein in SubtiPathways: Purine salvage, Purine synthesis, Nucleotides (regulation) | |
| MW, pI | 18 kDa, 4.701 |
| Gene length, protein length | 510 bp, 170 aa |
| Immediate neighbours | relA, yrvE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, universally conserved proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27610
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate (according to Swiss-Prot)
- Protein family: purine/pyrimidine phosphoribosyltransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 2DY0 (from Escherichia coli k12, 56% identity, 66% similarity)
- UniProt: O34443
- KEGG entry: [3]
- E.C. number: 2.4.2.7
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
