RodZ

• Description: required for cell shape determination
  
  

Gene name	rodZ
Synonyms	ymfM
Essential	no
Product	morphogenic protein
Function	required for cell shape determination
MW, pI	23 kDa, 4.679
Gene length, protein length	639 bp, 213 aa
Immediate neighbours	ymfL, pgsA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell shape, membrane proteins

The gene

Basic information

• Locus tag: BSU16910

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • part of the cell wall biosynthetic complex PubMed

• Localization: membrane protein (according to Swiss Prot)

Database entries

• Structure:

• UniProt: O31771

• KEGG entry: [2]

• E.C. number:

Additional information

overexpression results in growth inhibition in minimal medium (in the absence of Mg2+ ) PubMed

Expression and regulation

• Operon:

• Expression browser: rodZ PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Adriano Henriques, Lisbon, Portugal homepage

References

Ethan C Garner, Remi Bernard, Wenqin Wang, Xiaowei Zhuang, David Z Rudner, Tim Mitchison
Coupled, circumferential motions of the cell wall synthesis machinery and MreB filaments in B. subtilis.
Science: 2011, 333(6039);222-5
[PubMed:21636745] [WorldCat.org] [DOI] (I p)

Julia Domínguez-Escobar, Arnaud Chastanet, Alvaro H Crevenna, Vincent Fromion, Roland Wedlich-Söldner, Rut Carballido-López
Processive movement of MreB-associated cell wall biosynthetic complexes in bacteria.
Science: 2011, 333(6039);225-8
[PubMed:21636744] [WorldCat.org] [DOI] (I p)

S Anisah Alyahya, Roger Alexander, Teresa Costa, Adriano O Henriques, Thierry Emonet, Christine Jacobs-Wagner
RodZ, a component of the bacterial core morphogenic apparatus.
Proc Natl Acad Sci U S A: 2009, 106(4);1239-44
[PubMed:19164570] [WorldCat.org] [DOI] (I p)