YcbJ

• Description: similar to macrolide 2'-phosphotransferase
  
  

Gene name	ycbJ
Synonyms
Essential	no
Product	unknown
Function	unknown
MW, pI	34 kDa, 4.565
Gene length, protein length	918 bp, 306 aa
Immediate neighbours	ycbH, rtpA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

resistance against toxins/ antibiotics

This gene is a member of the following regulons

AbrB regulon, YcbG regulon

The gene

Basic information

• Locus tag: BSU02520

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: aminoglycoside phosphotransferase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P42242

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ycbC-ycbD-ycbE-ycbF-ycbG-ycbH-ycbJ PubMed

• Expression browser: ycbJ PubMed

• Sigma factor:

• Regulation:
  • induced by D-glucarate/galactarate (YcbG) PubMed
  • repressed during logarithmic phase (AbrB) PubMed

• Regulatory mechanism:
  • YcbG: transcription repression PubMed
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Allison V Banse, Arnaud Chastanet, Lilah Rahn-Lee, Errett C Hobbs, Richard Losick
Parallel pathways of repression and antirepression governing the transition to stationary phase in Bacillus subtilis.
Proc Natl Acad Sci U S A: 2008, 105(40);15547-52
[PubMed:18840696] [WorldCat.org] [DOI] (I p)

Shigeo Hosoya, Kunio Yamane, Michio Takeuchi, Tsutomu Sato
Identification and characterization of the Bacillus subtilis D-glucarate/galactarate utilization operon ycbCDEFGHJ.
FEMS Microbiol Lett: 2002, 210(2);193-9
[PubMed:12044674] [WorldCat.org] [DOI] (P p)