Difference between revisions of "LacR"
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Revision as of 06:51, 17 April 2012
- Description: transcriptional repressor of the beta-galactosidase gene
| Gene name | lacR |
| Synonyms | yvfJ |
| Essential | no |
| Product | transcriptional repressor (LacI family) |
| Function | regulation of utilization of polymeric carbohydrates |
| MW, pI | 37 kDa, 5.396 |
| Gene length, protein length | 990 bp, 330 aa |
| Immediate neighbours | cycB, lutR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
utilization of specific carbon sources, transcription factors and their control
This gene is a member of the following regulons
The LacR regulon:
The gene
Basic information
- Locus tag: BSU34170
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: LacI family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O07008
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: GP815 (spc) available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
R A Daniel, J Haiech, F Denizot, J Errington
Isolation and characterization of the lacA gene encoding beta-galactosidase in Bacillus subtilis and a regulator gene, lacR.
J Bacteriol: 1997, 179(17);5636-8
[PubMed:9287030]
[WorldCat.org]
[DOI]
(P p)
J Errington, C H Vogt
Isolation and characterization of mutations in the gene encoding an endogenous Bacillus subtilis beta-galactosidase and its regulator.
J Bacteriol: 1990, 172(1);488-90
[PubMed:2104611]
[WorldCat.org]
[DOI]
(P p)
