NhaK

• Description: cation/H+ antiporter
  
  

Gene name	nhaK
Synonyms	yvgP
Essential	no
Product	cation/H+ antiporter
Function	monovalent cation export
MW, pI	75 kDa, 9.222
Gene length, protein length	2010 bp, 670 aa
Immediate neighbours	yvgO, cysJ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), membrane proteins

The gene

Basic information

• Locus tag: BSU33420

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: export of Na(+), K(+), Li(+), Rb(+)

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O32212

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: nhaK PubMed

• Expression browser: nhaK PubMed

• Sigma factor:

• Regulation: constitutive, expression increases in the presence of Na(+) and K(+) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Makoto Fujisawa, Ayumi Kusumoto, Yuko Wada, Takahiro Tsuchiya, Masahiro Ito
NhaK, a novel monovalent cation/H+ antiporter of Bacillus subtilis.
Arch Microbiol: 2005, 183(6);411-20
[PubMed:16021482] [WorldCat.org] [DOI] (P p)