Difference between revisions of "YqeH"

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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yqeH_2645490_2646590_-1 yqeH] {{PubMed|22383849}}
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=Biological materials =
 
=Biological materials =

Revision as of 11:45, 16 April 2012

  • Description: assembly/ stability of the 30S subunit of the ribosome, assembly of the 70S ribosome

Gene name yqeH
Synonyms
Essential yes PubMed
Product GTPase
Function ribosome assembly
MW, pI 40 kDa, 6.009
Gene length, protein length 1098 bp, 366 aa
Immediate neighbours aroD, yqeG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YqeH context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

translation, essential genes, GTP-binding proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU25670

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Binds and hydrolyzes GTP and readily exchanges GDP for GTP
  • Protein family: Era/Obg family

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3EC1 (Geobacillus stearothermophilus)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Naotake Ogasawara, Nara, Japan

Your additional remarks

References

Reviews

Natalie Verstraeten, Maarten Fauvart, Wim Versées, Jan Michiels
The universally conserved prokaryotic GTPases.
Microbiol Mol Biol Rev: 2011, 75(3);507-42, second and third pages of table of contents
[PubMed:21885683] [WorldCat.org] [DOI] (I p)

Robert A Britton
Role of GTPases in bacterial ribosome assembly.
Annu Rev Microbiol: 2009, 63;155-76
[PubMed:19575570] [WorldCat.org] [DOI] (I p)

Original publications

Baskaran Anand, Parag Surana, Balaji Prakash
Deciphering the catalytic machinery in 30S ribosome assembly GTPase YqeH.
PLoS One: 2010, 5(4);e9944
[PubMed:20376346] [WorldCat.org] [DOI] (I e)

Baskaran Anand, Parag Surana, Sagar Bhogaraju, Sushmita Pahari, Balaji Prakash
Circularly permuted GTPase YqeH binds 30S ribosomal subunit: Implications for its role in ribosome assembly.
Biochem Biophys Res Commun: 2009, 386(4);602-6
[PubMed:19540197] [WorldCat.org] [DOI] (I p)

Pek Chin Loh, Takuya Morimoto, Yoshitaka Matsuo, Taku Oshima, Naotake Ogasawara
The GTP-binding protein YqeH participates in biogenesis of the 30S ribosome subunit in Bacillus subtilis.
Genes Genet Syst: 2007, 82(4);281-9
[PubMed:17895579] [WorldCat.org] [DOI] (P p)

William C Uicker, Laura Schaefer, Mark Koenigsknecht, Robert A Britton
The essential GTPase YqeH is required for proper ribosome assembly in Bacillus subtilis.
J Bacteriol: 2007, 189(7);2926-9
[PubMed:17237168] [WorldCat.org] [DOI] (P p)

Takuya Morimoto, Pek Chin Loh, Tomohiro Hirai, Kei Asai, Kazuo Kobayashi, Shigeki Moriya, Naotake Ogasawara
Six GTP-binding proteins of the Era/Obg family are essential for cell growth in Bacillus subtilis.
Microbiology (Reading): 2002, 148(Pt 11);3539-3552
[PubMed:12427945] [WorldCat.org] [DOI] (P p)