YcnD

• Description: NADPH-FMN oxidoreductase, delivers reduced FMN to enzymes that require the reduced cofactor for activity
  
  

Gene name	ycnD
Synonyms
Essential	no
Product	NADPH-FMN oxidoreductase
Function	delivery of FMN to enzymes
MW, pI	27 kDa, 5.081
Gene length, protein length	747 bp, 249 aa
Immediate neighbours	ycnC, ycnE
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

electron transport/ other

The gene

Basic information

• Locus tag: BSU03860

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: flavin oxidoreductase frp family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1ZCH

• UniProt: P94424

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ycnE-ycnD PubMed

• Expression browser: ycnD PubMed

• Sigma factor:

• Regulation:
  • induced by chromanon PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Van Duy Nguyen, Carmen Wolf, Ulrike Mäder, Michael Lalk, Peter Langer, Ulrike Lindequist, Michael Hecker, Haike Antelmann
Transcriptome and proteome analyses in response to 2-methylhydroquinone and 6-brom-2-vinyl-chroman-4-on reveal different degradation systems involved in the catabolism of aromatic compounds in Bacillus subtilis.
Proteomics: 2007, 7(9);1391-408
[PubMed:17407181] [WorldCat.org] [DOI] (P p)

Alexander Morokutti, Andrzej Lyskowski, Sonja Sollner, Eva Pointner, Teresa B Fitzpatrick, Christoph Kratky, Karl Gruber, Peter Macheroux
Structure and function of YcnD from Bacillus subtilis, a flavin-containing oxidoreductase.
Biochemistry: 2005, 44(42);13724-33
[PubMed:16229462] [WorldCat.org] [DOI] (P p)