Difference between revisions of "PdaC"

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* '''Description:''' extracellular Dnase, peptidoglycan deacetylase <br/><br/>
+
* '''Description:''' peptidoglycan deacetylase C <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || extracellular Dnase
+
|style="background:#ABCDEF;" align="center"| '''Product''' || polysaccharide deacetylase C
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || degradation of DNA
+
|style="background:#ABCDEF;" align="center"|'''Function''' || cell wall modification
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 53 kDa, 9.105   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 53 kDa, 9.105   
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* '''Locus tag:''' BSU12100
 
* '''Locus tag:''' BSU12100
 
[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yjeA_1281128_1282531_1 Expression]
 
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* sensitive to lysozyme treatment  {{PubMed|22277649}}
  
 
=== Database entries ===
 
=== Database entries ===
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=== Additional information===
 
=== Additional information===
 
 
  
  
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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
 +
** deacetylates N-acetylmuramic acid (MurNAc) but not GlcNAc from peptidoglycan {{PubMed|22277649}}
  
 
* '''Protein family:''' polysaccharide deacetylase family (according to Swiss-Prot)
 
* '''Protein family:''' polysaccharide deacetylase family (according to Swiss-Prot)
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
 
+
** K(m)=4.8 mM and k(cat)=0.32 s(-1) (toward ''B. subtilis'' peptidoglycan) {{PubMed|22277649}}
 
* '''Domains:'''  
 
* '''Domains:'''  
  
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=References=
 
=References=
  
<pubmed>17878218,17581128,, </pubmed>
+
<pubmed>17878218,17581128, 22277649</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 18:25, 27 January 2012

  • Description: peptidoglycan deacetylase C

Gene name yjeA
Synonyms
Essential no
Product polysaccharide deacetylase C
Function cell wall modification
MW, pI 53 kDa, 9.105
Gene length, protein length 1401 bp, 467 aa
Immediate neighbours cotT, yjfA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YjeA context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

cell wall/ other

This gene is a member of the following regulons

WalR regulon

The gene

Basic information

  • Locus tag: BSU12100

Phenotypes of a mutant

  • sensitive to lysozyme treatment PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • deacetylates N-acetylmuramic acid (MurNAc) but not GlcNAc from peptidoglycan PubMed
  • Protein family: polysaccharide deacetylase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
    • K(m)=4.8 mM and k(cat)=0.32 s(-1) (toward B. subtilis peptidoglycan) PubMed
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References