TlpA

• Description: membrane-bound chemotaxis receptor, methyl-accepting chemotaxis protein
  
  

Gene name	tlpA
Synonyms
Essential	no
Product	methyl-accepting chemotaxis protein
Function	control of chemotaxis
MW, pI	72 kDa, 4.906
Gene length, protein length	1986 bp, 662 aa
Immediate neighbours	mcpA, mcpB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

motility and chemotaxis, membrane proteins

This gene is a member of the following regulons

AbrB regulon, SigD regulon

The gene

Basic information

• Locus tag: BSU31250

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane PubMed, Polar (Septum) PubMed

Database entries

• Structure:

• UniProt: P39216

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: tlpA-mcpA PubMed

• Sigma factor: SigD PubMed

• Regulation:

• Regulatory mechanism:
  • AbrB: transcription repression PubMed

• Additional information:
  • in minimal medium, TlpA is present with 2,100 +/- 890 molecules per cell PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed