GlnQ

• Description: glutamine ABC transporter (ATP-binding protein) ,
  
  

Gene name	glnQ
Synonyms
Essential	no
Product	glutamine ABC transporter (ATP-binding protein) ,
Function	glutamine uptake
Interactions involving this protein in SubtInteract: GlnQ
Metabolic function and regulation of this protein in SubtiPathways: Ammonium/ glutamate
MW, pI	27 kDa, 6.434
Gene length, protein length	726 bp, 242 aa
Immediate neighbours	yrrI, glnH
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

ABC transporters, biosynthesis/ acquisition of amino acids, utilization of amino acids, membrane proteins, sporulation proteins

This gene is a member of the following regulons

SigE regulon, TnrA regulon

The gene

Basic information

• Locus tag: BSU27430

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • GlnQ-(GlnM-GlnP)-GlnH PubMed

• Localization: attached to the membrane via GlnM-GlnP PubMed

Database entries

• Structure: 2Q0H (complex with ADP-Mg2+, Geobacillus stearothermophilus, 59% identity)

• UniProt: O34677

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: glnQ-glnH-glnM-glnP PubMed

• Sigma factor:

• Regulation:
  • expressed in the absence of good nitrogen sources (glutamine or ammonium) (TnrA) PubMed
  • expressed during sporulation (SigE) PubMed

• Regulatory mechanism:
  • TnrA: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Ken-ichi Yoshida, Hirotake Yamaguchi, Masaki Kinehara, Yo-hei Ohki, Yoshiko Nakaura, Yasutaro Fujita
Identification of additional TnrA-regulated genes of Bacillus subtilis associated with a TnrA box.
Mol Microbiol: 2003, 49(1);157-65
[PubMed:12823818] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)