Difference between revisions of "SknR"

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(The SknR regulon: yqaF-yqdA-yqaG-yqaH-yqaI-yqaJ-yqaK-yqaL-yqaM-yqaN)
(Basic information/ Evolution)
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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' binds the yqaF promoter region to repress transcription of the ''[[yqaF]]-[[yqdA]]-[[yqaG]]-[[yqaH]]-[[yqaI]]-[[yqaJ]]-[[yqaK]]-[[yqaL]]-[[yqaM]]-[[yqaN]]'' operon {{PubMed|20889742}}  
+
* '''Catalyzed reaction/ biological activity:''' binds the yqaF promoter region to repress transcription of the ''[[yqaF]]-[[yqdA]]-[[yqaG]]-[[yqaH]]-[[yqaI]]-[[yqaJ]]-[[yqaK]]-[[yqaL]]-[[yqaM]]-[[yqzO]]-[[yqaN]]'' operon {{PubMed|20889742}}  
  
 
* '''Protein family:'''
 
* '''Protein family:'''

Revision as of 08:46, 17 October 2011

Gene name sknR
Synonyms yqaE
Essential no
Product transcription repressor
Function control of prophage gene expression
MW, pI 13 kDa, 5.42
Gene length, protein length 348 bp, 116 aa
Immediate neighbours yqaF, yqaD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YqaE context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

transcription factors and their control, Skin element

This gene is a member of the following regulons

The SknR regulon: yqaF-yqdA-yqaG-yqaH-yqaI-yqaJ-yqaK-yqaL-yqaM-yqzO-yqaN

The gene

Basic information

  • Locus tag: BSU26350

Phenotypes of a mutant

  • essential in the wild type background (due to overexpression of the toxic proteins YqaH and YqaM) PubMed
  • no phenotype if deleted with the complete skin element PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Tatsu Kimura, Yukie Amaya, Kazuo Kobayashi, Naotake Ogasawara, Tsutomu Sato
Repression of sigK intervening (skin) element gene expression by the CI-like protein SknR and effect of SknR depletion on growth of Bacillus subtilis cells.
J Bacteriol: 2010, 192(23);6209-16
[PubMed:20889742] [WorldCat.org] [DOI] (I p)