Difference between revisions of "CsrA"
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=== Additional information=== | === Additional information=== | ||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| + | ** [[CsrA]] binds the ''[[hag]]'' mRNA to inhibit translation {{PubMed|21895793}} | ||
* '''Protein family:''' csrA family (according to Swiss-Prot) | * '''Protein family:''' csrA family (according to Swiss-Prot) | ||
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| + | ** [[CsrA]] is sequestered by interaction with [[FliW]] (the two proteins form a conserved module in many bacteria) {{PubMed|21895793}} | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
** [[CsrA]]-[[RsmY]] (hypothetical) | ** [[CsrA]]-[[RsmY]] (hypothetical) | ||
| + | ** [[FliW]]-[[CsrA]] {{PubMed|21895793}} | ||
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
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=== Additional information=== | === Additional information=== | ||
| + | * [[CsrA]] and [[FliW]] form a conserved module in many bacteria {{PubMed|21895793}} | ||
=Expression and regulation= | =Expression and regulation= | ||
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<pubmed>19385727, </pubmed> | <pubmed>19385727, </pubmed> | ||
==Original Publications== | ==Original Publications== | ||
| − | <pubmed>16822857,17555441 8969505, </pubmed> | + | <pubmed>16822857,17555441 8969505, 21895793 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:55, 16 September 2011
- Description: similar to E. coli carbon storage regulator
| Gene name | csrA |
| Synonyms | yviG |
| Essential | no |
| Product | unknown |
| Function | unknown |
| Interactions involving this protein in SubtInteract: CsrA | |
| MW, pI | 8 kDa, 6.09 |
| Gene length, protein length | 222 bp, 74 aa |
| Immediate neighbours | hag, fliW |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The CsrA regulon: hag
The gene
Basic information
- Locus tag: BSU35370
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: csrA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 1T3O
- UniProt: P33911
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: csrA PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: GP469 (spc), available in Stülke lab
- Expression vector:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Paul Babitzke, Carol S Baker, Tony Romeo
Regulation of translation initiation by RNA binding proteins.
Annu Rev Microbiol: 2009, 63;27-44
[PubMed:19385727]
[WorldCat.org]
[DOI]
(I p)
Original Publications
