Difference between revisions of "RecN"
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
| − | * '''Localization:''' | + | * '''[[Localization]]:''' |
| + | ** nucleoid (Multiple) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed] | ||
| + | ** evenly distributed in growing cells {{PubMed|21859751}} | ||
| + | ** upon DNA damage, RecN forms a single focus per nucleoid {{PubMed|21859751}} | ||
=== Database entries === | === Database entries === | ||
Revision as of 14:02, 24 August 2011
- Description: DNA repair and genetic recombination
| Gene name | recN |
| Synonyms | |
| Essential | no |
| Product | unknown |
| Function | DNA repair and genetic recombination |
| MW, pI | 64 kDa, 4.802 |
| Gene length, protein length | 1728 bp, 576 aa |
| Immediate neighbours | spoIVB, ahrC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
DNA repair/ recombination, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24240
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: recN family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P17894
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Peter Graumann, Freiburg University, Germany homepage
Your additional remarks
References
Reviews
Original publications
Additional publications: PubMed
Dawit Kidane, Begoña Carrasco, Candela Manfredi, Katharina Rothmaier, Silvia Ayora, Serkalem Tadesse, Juan C Alonso, Peter L Graumann
Evidence for different pathways during horizontal gene transfer in competent Bacillus subtilis cells.
PLoS Genet: 2009, 5(9);e1000630
[PubMed:19730681]
[WorldCat.org]
[DOI]
(I p)
Lyle A Simmons, Alexi I Goranov, Hajime Kobayashi, Bryan W Davies, Daniel S Yuan, Alan D Grossman, Graham C Walker
Comparison of responses to double-strand breaks between Escherichia coli and Bacillus subtilis reveals different requirements for SOS induction.
J Bacteriol: 2009, 191(4);1152-61
[PubMed:19060143]
[WorldCat.org]
[DOI]
(I p)
Humberto Sanchez, Paula P Cardenas, Shige H Yoshimura, Kunio Takeyasu, Juan C Alonso
Dynamic structures of Bacillus subtilis RecN-DNA complexes.
Nucleic Acids Res: 2008, 36(1);110-20
[PubMed:17999999]
[WorldCat.org]
[DOI]
(I p)
Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537]
[WorldCat.org]
[DOI]
(P p)
Humberto Sanchez, Dawit Kidane, M Castillo Cozar, Peter L Graumann, Juan C Alonso
Recruitment of Bacillus subtilis RecN to DNA double-strand breaks in the absence of DNA end processing.
J Bacteriol: 2006, 188(2);353-60
[PubMed:16385024]
[WorldCat.org]
[DOI]
(P p)
Humberto Sanchez, Juan C Alonso
Bacillus subtilis RecN binds and protects 3'-single-stranded DNA extensions in the presence of ATP.
Nucleic Acids Res: 2005, 33(7);2343-50
[PubMed:15849320]
[WorldCat.org]
[DOI]
(I e)
B E Van Hoy, J A Hoch
Characterization of the spoIVB and recN loci of Bacillus subtilis.
J Bacteriol: 1990, 172(3);1306-11
[PubMed:2106508]
[WorldCat.org]
[DOI]
(P p)
